"These findings from the present study suggest that trenbolone use may be linked to increased verbal aggression among males using AAS, particularly at higher doses. This extends on current literature highlighting the potential effects of AAS on non-physical aggression (Chegeni, Pallesen, et al., 2021), of which trenbolone is a potent example. Notably, the HAARLEM study, which also used the Buss and Perry Aggression Questionnaire, observed an increase in the 'Anger' subscale among people using AAS but did not find elevated physical aggression (Smit et al., 2021). Additionally, one participant in the HAARLEM study discontinued trenbolone use due to agitation, which resonates with our findings that trenbolone may exacerbate psychological distress and aggression. This underscores the importance of considering trenbolone alongside other AAS when examining the impact on aggression and violence. It raises the possibility that trenbolone's effects might have been confounding the understanding of other AAS effects in previous studies given that scholarly work regarding AAS often remains generalised. Recent research indicates that the harms associated with these drugs may vary depending on the specific type used (Piatkowski et al., 2023b, 2024; Underwood, 2022). Our data supports preliminary qualitative work (Piatkowski et al., 2023b) in suggesting that AAS could be categorised into groups based on their associated risks. For example, 'higher-risk' drugs like trenbolone may promote more severe physical and psychosocial effects (Aknouche et al., 2021; Piatkowski et al., 2023b, 2024; Rahmani et al., 2014; Underwood, 2022; Zelleroth et al., 2024), while lower-risk drugs like testosterone pose milder risks (Eu et al., 2023a,b). However, further consideration and differentiation of the multitude of AAS are needed to provide a more nuanced understanding of their effects. Therefore, moving forward, there is a critical need for research to differentiate between various AAS types and to conduct more comprehensive studies."
Piatkowski T, De Andrade D, Neumann D, Tisdale C, Dunn M. Examining the association between trenbolone, psychological distress, and aggression among males who use anabolic-androgenic steroids. Int J Drug Policy. Published online October 31, 2024. doi:10.1016/j.drugpo.2024.104636