"Drug quantity varied considerably between fentanyl and its analogues.134 The drug quantity for fentanyl offenders in fiscal year 2019 ranged from 100 micrograms to 36 kilograms. The average drug weight for the fentanyl offenders was 1.7 kilograms, and the median drug weight was 160 grams (Figure 15).
"The drug quantity for fentanyl analogue offenders ranged from 70 milligrams to 62.1 kilograms. The average amount of fentanyl analogue trafficked was 764 grams and the median weight was 75 grams.
"These weights are not limited to the quantity of pure fentanyl or one of its analogues involved in an offense135 as these substances are often mixed with other drugs or cutting agents,136 or are pressed into pills with inert fillers. As discussed above, under the drug trafficking guidelines, the entire weight of any mixture or substance containing a detectable amount of the controlled substance is assigned to the controlled substance that results in the greater offense level.137"
Fentanyl and Fentanyl Analogues: Federal Trends and Trafficking Patterns." US Sentencing Commission. January 2021.