"Synthetic cannabinoid receptor agonists (hereafter synthetic cannabinoids) are a chemically diverse group of synthesised compounds that often act on similar receptors to those acted on by Δ-9-tetrahydronnabinol in cannabis. Powders are typically dissolved in solvent, sprayed on inert plant material and then smoked, and are often sold as commercial mixtures (eg, Spice, Kronic).12 Other forms and routes of administration include ingestion of pills or powders, and vaping using solutions containing synthetic cannabinoids. Effects can be similar to those resulting from use of cannabis (eg, euphoria, sedation, and drowsiness), but are typically more severe and sometimes unique from cannabis.13"
Amy Peacock, PhD, Raimondo Bruno, PhD, Natasa Gisev, PhD, Prof Louisa Degenhardt, PhD, Prof Wayne Hall, PhD, Roumen Sedefov, MD, et al. New psychoactive substances: challenges for drug surveillance, control, and public health responses. The Lancet. Volume 394, Issue 10209, p1668-1684, November 02, 2019. Published:October 23, 2019.