MDMA Therapy and Substance Abuse

"The data we obtained about illicit drug use from the LTFU [Long Term Follow Up] Questionnaire supports the hypothesis that MDMA can be administered in a clinical setting with minimal risk that the subjects will subsequently seek out and self-administer 'street ecstasy,' or become dependent on the drug. This is consistent with the comments from many study subjects, who expressed the strong opinion that the therapeutic setting and close follow-up were essential elements of the treatment, and they did not think MDMA should be used without this level of clinical monitoring and therapeutic support."


Mithoefer, Michael C., et al., "Durability of improvement in posttraumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3,4-methylenedioxymethamphetamine-assisted psychotherapy: a prospective long-term follow-up study," Journal of Psychopharmacology, published online Nov. 20, 2012, DOI: 10.1177/0269881112456611.